EASO 2023: The Roczen Programme - A digitally-enabled, medically-led intervention for obesity and T2DM: outcomes at 1 year
The Roczen Programme - a digitally-enabled, medically-led intervention for obesity and T2DM: outcomes at 1 year
Laura Falvey1, Ling Chow1, Adrian Brown,1,2, Dipesh Patel1,2,3, Jonathan TC Kwan1,4, Siri Steinmo1,5, and Barbara McGowan1,7
1Reset Health Ltd, London, UK
2University College London, London, UK
3Royal Free Hospital, London, UK
4Darent Valley Hospital, Kent, UK
5UCLH, London, UK
6Guys & St Thomas’s Hospital, London, UK
Introduction
Obesity and type 2 diabetes (T2D) remain major global health challenges. Continuous energy restriction can help people lose weight, but more recently time-restricted eating (TRE) has been shown to be an alternative method for weight loss. Limited data exists about its effectiveness in a real-world setting using digital delivery. Reset Health is a technology-enabled clinical programme designed for people living with obesity, T2D, and other complications. The aim was to assess the impact of the Reset Health programme on weight, metabolic parameters, and other health-related outcomes at 1 year.
Method
732 adults enrolled in the programme. Mean age 47.2±10.5yrs, mean BMI 34.9±6.3kg/m2, Ethnicity 58% White Ethnicity, 11% Indian, 10% Black African, 7% Black Caribbean, 14% Other. 21% (n=155) had pre-diabetes (n=65; 8.9%) or T2D (n=90; 12.3%). Participants were enrolled in a TRE, low-carbohydrate, moderate protein plan which was delivered by clinicians and mentors. Participants received dietary guidance, goal setting, feedback, and social support. Available data were analysed at 52-weeks for completers and reported using mean±SD.
Results
Weight loss at 52 weeks was 8.9±7.0kg (n=121), and 71% lost ≥ 5% of body weight. Waist circumference decreased by 10.9±13.6cm (n=101). There was a 10.8 and 15.1 mmol/mol reduction in HbA1c at 24 and 52 weeks respectively for those with T2DM. There were small reductions in systolic and diastolic blood pressure. There was a reduction in PHQ-9 depression scores, and no increase in binge eating as measured by Binge-Eating Scales. Retention rates at 24 weeks and 52 weeks were 69% and 43% respectively.
Conclusions
Evaluation of Roczen, a digitally enabled, medically led, time restricted eating programme within a real-world population demonstrated significant improvements in weight loss and health-related outcomes which were sustained at 1 year with good retention rates.
Conflicts of interest: AB, DP, JK, SS, BM are on the medical advisory board and are shareholders in Reset Health. LC, LF are employed and are shareholders at Reset Health.
starting with Type 2 diabetes and obesity.
